In two weeks, 34 Palestinians were killed by Israeli fire, including 27 during protests.
But the Israeli military said at least 10,000 people demonstrated in five locations.
An Israeli reporter who requested anonymity told Al-Monitor that the reason why journalists were targeted that particular week, unlike the previous week during protests, might be connected to concerns about being targeted by worldwide institutions.
Clashes between stone-throwing Palestinians and Israeli soldiers took place in multiple spots along the border while tear gas and plumes of black smoke from burning tyres filled the air in some areas. Greenblatt also serves as Donald Trump's Special Representative for International Negotiations.
An Israeli Defence Forces (IDF) official, speaking on condition of anonymity, refused to detail specific rules for engagement that admitted live sniper fire or say how many people had been shot.
An Israeli military spokesman on Friday said Palestinian demonstrators launched explosives and incendiary devices along the defensive barrier dividing Gaza from Israel. Hundreds more were reported injured from inhaling tear gas.
Numerous injuries were the result of live ammunition and tear gas fired by Israeli soldiers, the ministry said.
Yair Lapid, the leader of Israel's centrist Yesh Atid party, called Hamas a "despicable terror organization" and accused it of exploiting civilians.
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Israel did not confirm these figures.
People attend a protest against the killing of a fellow journalist Palestinian Yasser Murtaja on April 11, 2018 in Istanbl.
The six-week anti-Israel protest in Gaza, known as the "Great March of Return", started on March 30, and is expected to peak on May 15.
Today's march has been named "protest to burn the Israeli flag and hoist the Palestinian flag".
Israel says its forces have opened fire to stop attempts to harm soldiers, damage the fence, infiltrate Israel and attempt to carry out attacks. "As additional protests are planned for the coming days, the Israel Defense Forces should exercise restraint and respect the rights of Palestinians to peacefully protest".
The idea of mass protests was initially floated by Palestinian social media activists in Gaza, but was later co-opted by Hamas, which avowedly seeks Israel's destruction, with the backing of smaller terror groups.
Some 70 percent of the Gazan population are refugees, meaning they or their grandparents fled or were expelled from towns, villages, and cities inside the territory that become Israel in 1948.
The Palestine Red Crescent Society, a humanitarian organisation, has said one of its medics was shot in the knee.