Conte threw on Alvaro Morata, Willian and Pedro, but it was to little avail as the hosts held firm.
The top-four was a remote possibility before kick-off but that was barely a secondary concern here, with a shot at redemption and a piece of silverware within reach next weekend.
Conte is adamant that the constant talk over his position at Stamford Bridge has not upset him and has caused no issues for his side on the back of last season's title success.
Eden Hazard has been in decent form of late, but was poor against Newcastle.
Frenchman Wenger, who is leaving the club after nearly 22 years in charge, was given a guard of honour by both sets of players before the kickoff and then walked to the visiting Arsenal supporters to acknowledge them.
Guardiola said: "This season they were a big contender and they will be again next season". A return to Europe, however, isn't.
Former Labour minister Dame Tessa Jowell dies following brain cancer battle
He told the Press Association: "She did two things which were really important in that early stage". The former cabinet minister was diagnosed with a gliobastoma multiforme brain tumour last May.
"We're still talking and we will see what happens".
Now at Monaco, Emenalo was a key figure during his ten-year tenure with Chelsea and was one of the reasons why Antonio Conte did so well in his debut season.
That makes Chelsea's lifeless display all the more worrying.
"Newcastle outplayed us and they deserved to win".
Antonio Conte looks set for the exit door at Chelsea.
"We didn't lose our place in Champions League today, but only in the last two game".
Everyone knows Mourinho is a divisive character.
He indicated that it is for the club to understand how damaging or not damaging it will be for Chelsea. Conte's troubles are a very big flashing distress signal.
In other Premier League clash Tottenham came from behind to win Leicester City 5 - 4 in an epic nine goals thriller.
"Are Chelsea are in a better place now?" Their issues go beyond the manager.