People living in villages near the volcano didn't have much time or warning to escape the lava flow, reports CBS News correspondent Don Dahler. "We are going to have to resort to other methods. and if possible take DNA samples to identify them".
So far, 15 people been have been hospitalised, including 12 children, some of whom suffered severe burns, according to the Health Ministry.
This is when a violently erupted mass of rock fragments and hot gas finds itself too dense to rise as an ash column and instead cascades down the volcano's slopes.
The Volcan de Fuego, or "volcano of fire", exploded in a hail of ash and molten rock shortly before noon Sunday, blanketing nearby villages in heavy ash.
"It's a river of lava that overflowed its banks and affected the El Rodeo village".
As of Monday afternoon, Guatemala's national emergency response agency said more than 3,200 people had been evacuated with more than 1.7 million people affected. Guatemala City's global airport was closed due to the danger to planes.
People were working to clean ash off the runways to get the airport operating again.
"The firemen say they can hear people screaming, but they can't go to help them because the mud is blocking the roads", AP correspondent Sonia Perez said from one of the hardest hit areas.
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You could have taken the fight but you are the one who pulled out, not me. We didn't get the result but I feel it's a great time to come back.
Sergio Cabanas of the National Disaster prevention committee spoke to Reuters and informed that people have been burned and killed including a member of his staff.
Police officers carry a wounded man after the eruption of the Fuego Volcano, in El Rodeo village, Escuintla department south of Guatemala City on June 3, 2018.
"Conred (the disaster agency) never told us to leave".
Rescue teams have been searching frantically for survivors and victims in the lava-ravaged landscape.
The country's disaster agency said Monday that the death toll remains at 25, though there are apparently people still unaccounted for.
Fuego Volcano is famous for being nearly constantly active at a low level.
This is Guatemala's deadliest such event since 1902, when an eruption of the Santa Maria volcano killed thousands of people.
Israel and Guatemala have grown increasingly close in recent years. The Palestinians seek its eastern sector as capital of their hoped-for state.
Volcan de Fuego, whose name means "Volcano of Fire", spewed an 8-kilometer (5-mile) stream of red hot lava and belched a thick plume of black smoke and ash that rained onto the capital and other regions. Seven deaths were confirmed previously.