"China has consistently opposed unilateral sanctions and long-armed jurisdiction", the Chinese foreign ministry said.
The first round of USA sanctions reinstated against Iran this week makes clear to the Islamic Republic the Trump administration's willingness to financially squeeze the regime until it curbs its destabilizing behavior, according to regional experts.
And he added Iran's power has grown since its leaders signed the Joint Comprehensive Plan of Action, the official name of the non-proliferation nuclear deal, in 2015. But that has proved hard: European companies have quit Iran, arguing that they can not risk their USA business.
"America has zigzagged constantly, so now no one trusts them", he said.
The chief executive of reinsurance group Munich Re said it may abandon its Iran business under pressure from the United States, but described the operation as very small.
Turkey, however, said it would continue to buy natural gas from Iran.
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Iran's foreign minister Javad Zarif turned the tables on Washington's efforts to isolate the regime, saying Monday that it is in fact the US, Israel, and Saudi Arabia who are isolated in their hostility towards Iran.
US officials have said in recent weeks that they aim to pressure countries to stop buying oil from Iran in a bid to force Tehran to halt its nuclear and missile programs and involvement in regional conflicts in Syria and Iraq.
"The countries now the U.S. is negotiating with have told Washington that they will continue their oil purchases from Iran", he explained.
Mr Zarif added the idea of halting the exports of Iran's most valuable goods "simplistic and impossible" and will lead to "consequences".
Just one day after the USA issued their first set of sanctions were issued, Ms Mogherini said: "We are doing our best to keep Iran in the deal, to keep Iran benefiting from the economic benefits that the agreement brings to the people of Iran, because we believe this is in the security interests of not only our region but also of the world". The Trump tactics have deepened an already serious economic crisis in Iran, fuelling protests around the country.
His visit to Iran is the first by a high-ranking DPRK delegation since August a year ago, when President of the Presidium of the Supreme People's Assembly Kim Yong Nam and vice foreign minister Choe Hui Chol spent several days in the country.
"If you stab someone with a knife and then you say you want talks, then the first thing you have to do is remove the knife", Rouhani said in a speech broadcast live on state television.