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An incident took place during the October 11 launch of a Soyuz spacecraft carrying two men to the International Space Station, with the status of the spacecraft and crew now unknown.

NASA astronaut Hague and Roscosmos' cosmnonaut Ovchinin lifted off as scheduled at 4:40 a.m. EDT Thursday from the Russia-leased Baikonur cosmodrome in Kazakhstan.

A capsule carrying the crew of a Russian Soyuz rocket that malfunctioned on lift-off has landed safely in Kazakhstan, Russian media report.

"We had an interruption on today's launch", a NASA commentator reported.

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NASA Television reported that the spacecraft was in a ballistic descent after apparently separating from the Soyuz rocket, making a return to Earth rather than heading to the International Space Station. "We are told the rescue forces are in communication with Nick Hague and Alexei Ovchinin and we are hearing they are in good condition".

The pair was set to dock at the orbiting outpost six hours after launch, but the booster rocket failed minutes after launch.

The rocket was carrying United States astronaut Nick Hague and Russian cosmonaut Alexei Ovchinin.

The Soyuz MS-10 spacecraft is seen moments after blastoff.