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Six people died and dozens were injured in a stampede when panic broke out during a rap concert at an Italian nightclub Saturday morning, the fire service said.

An Italian rapper was be performing on stage at the Lanterna Azzura nightclub in Corinaldo before sprayed a "noxious substance" similar to pepper spray ate around 12am GMT (1am local time).

One of dead was a mother of a teenager.

Fourteen of the injured were in serious condition, and 40 others less seriously injured, Mr Poggiali said.

This comes as 1,500 people were injured in Turin after a firecracker sparked a stampede at a screening of the Champions League final in June previous year. It said there were about 1,000 people in the club when the stampede began.

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The dead included three girls, two boys and a woman. At one point, one of the side barriers collapses under pressure and sends several people falling on each other.

ANSA earlier had reported that someone had sprayed an irritant, which triggered the panic. Italian Interior Minister Matteo Salvini said there possibly was a "stink" that could have been ammonia or another substance.

The boy, who was being treated at a hospital, said that at least one of the emergency exits was locked when he tried to flee. He said that when rescuers arrived, all the doors were open.

There was panic after pepper spray was sacked inside the club, according to the BBC, citing other reports.

Firefighters had concentrated on giving first aid to survivors, stretched out on the road outside the club, before starting their investigation, he added.